Fig. 1 · Structure
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RORγt inverse agonist 23
Cat. No.
A77572
CAS
2230779-18-5
RORγt Inverse Agonist
RORγt inverse agonist 23 is a potent and selective inverse agonist targeting the retinoic acid receptor-related orphan receptor gamma t (RORγt). This compound demonstrates significant biological activity as an immunomodulator, making it valuable in the investigation of autoimmune diseases and inflammatory disorders. Its oral bioavailability enhances its utility in preclinical studies and therapeutic research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 2230779-18-5 |
| Applications | RORγt Inverse Agonist |
| Formula | C26H33NO5S |
| Molecular Weight | 471.61 |
| SMILES | OC1C2=C(C=CC(S(N(C3=CC=C(CC)C=C3)C4CCC4)(=O)=O)=C2)OC(C5CCOCC5)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.