Fig. 1 · Structure
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RORγt inverse agonist 26
Cat. No.
A77585
CAS
2738333-10-1
RORγt Inverse Agonist
RORγt inverse agonist 26 is a potent inverse agonist of the RORγt receptor, crucial for modulating Th17 cell differentiation. This compound effectively inhibits the production of interleukin-17 (IL-17), making it valuable for research into inflammation and autoimmune disorders. Delving into RORγt functionality, this reagent is instrumental in therapeutic development and understanding immune system regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 2738333-10-1 |
| Applications | RORγt Inverse Agonist |
| Formula | C27H21F7N2O5S |
| Molecular Weight | 618.52 |
| SMILES | FC(C=C(C=C1)C(C(F)(F)F)(O)C(F)(F)F)=C1C(C=C2)=CC=C2NC([C@H]3C4=CC=C(S(C)(=O)=O)C=C4CN3C(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.