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RORγt inverse agonist 26

Catalog No.: A77585
RORγt Inverse Agonist
RORγt inverse agonist 26 is a potent inverse agonist of the RORγt receptor, crucial for modulating Th17 cell differentiation. This compound effectively inhibits the production of interleukin-17 (IL-17), making it valuable for research into inflammation and autoimmune disorders. Delving into RORγt functionality, this reagent is instrumental in therapeutic development and understanding immune system regulation.
RORγt inverse agonist 26 2738333-10-1 RORγt Inverse Agonist
Grouped product items
Size Price Stock Qty
25mg
$1,655.00
In stock
50mg
$2,115.00
In stock
100mg
$2,720.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRORγt inverse agonist 26 is a potent inverse agonist of the RORγt receptor, crucial for modulating Th17 cell differentiation. This compound effectively inhibits the production of interleukin-17 (IL-17), making it valuable for research into inflammation and autoimmune disorders. Delving into RORγt functionality, this reagent is instrumental in therapeutic development and understanding immune system regulation.
Product Information
Catalog NumA77585
FormulaC27H21F7N2O5S
Molecular Weight618.52
CAS Number2738333-10-1
SMILESFC(C=C(C=C1)C(C(F)(F)F)(O)C(F)(F)F)=C1C(C=C2)=CC=C2NC([C@H]3C4=CC=C(S(C)(=O)=O)C=C4CN3C(C)=O)=O
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Endocrinology-Hormones > ROR