Fig. 1 · Structure
Documents & Downloads
RORγt inverse agonist 28
Cat. No.
A77594
CAS
2741870-21-1
RORγt Inverse Agonist
RORγt inverse agonist 28 is a potent inverse agonist targeting the retinoic acid receptor-related orphan receptor gamma t (RORγt). It effectively regulates the differentiation of T helper 17 (Th17) cells and inhibits interleukin-17 (IL-17) production. This compound is valuable for research into inflammation and autoimmune diseases, providing insights into potential therapeutic approaches.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 2741870-21-1 |
| Applications | RORγt Inverse Agonist |
| Formula | C23H18Cl2F3NO5S |
| Molecular Weight | 548.36 |
| SMILES | FC(F)(F)OC1=C(C2=C(C=C(C=C2Cl)NC([C@H](C3=CC=C(C=C3)S(C)(=O)=O)CO)=O)Cl)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.