RORγt Inverse Agonist 3 is a selective and orally bioavailable inverse agonist of RORγ, exhibiting potent activity with EC50 values of 0.22 μM for human RORγ and 0.15 μM for RORγt in human IL-17 cells. This compound is useful for investigations into the regulation of immune responses and the role of RORγt in inflammatory diseases. Its ability to inhibit RORγt activity makes it a valuable tool for research into conditions such as autoimmune disorders and cancer.
RORγt Inverse Agonist 3 is a selective and orally bioavailable inverse agonist of RORγ, exhibiting potent activity with EC50 values of 0.22 μM for human RORγ and 0.15 μM for RORγt in human IL-17 cells. This compound is useful for investigations into the regulation of immune responses and the role of RORγt in inflammatory diseases. Its ability to inhibit RORγt activity makes it a valuable tool for research into conditions such as autoimmune disorders and cancer.
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