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RORγt inverse agonist 34

Name: RORγt inverse agonist 34
Brand: Adooq Bioscience
SKU: A77601
Availability: OutOfStock

Cat. No. A77601 CAS 2247604-77-7

RORγt Inverse Agonist

RORγt inverse agonist 34 is a selective inverse agonist of the retinoic acid receptor-related orphan receptor gamma t (RORγt), exhibiting an IC50 of 0.094 μM for the RORγt-LBD. This compound demonstrates significant biological activity in modulating RORγt signaling pathways, making it a valuable tool for research into psoriasis and related inflammatory conditions. Its use facilitates the exploration of therapeutic strategies targeting RORγt in the regulation of immune responses.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inverse Agonist
CAS Number	2247604-77-7
Applications	RORγt Inverse Agonist
Formula	C₃₁H₃₇N₃O₃S
Molecular Weight	531.71
SMILES	O=S(N1CCCC2=CC(NC3=CC4=C(C=C3)C(CCC4)=O)=CC=C21)(N(CC5=CC=C(C=C5)C(C)(C)C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.