RORγt inverse agonist 34 is a selective inverse agonist of the retinoic acid receptor-related orphan receptor gamma t (RORγt), exhibiting an IC50 of 0.094 μM for the RORγt-LBD. This compound demonstrates significant biological activity in modulating RORγt signaling pathways, making it a valuable tool for research into psoriasis and related inflammatory conditions. Its use facilitates the exploration of therapeutic strategies targeting RORγt in the regulation of immune responses.
RORγt inverse agonist 34 is a selective inverse agonist of the retinoic acid receptor-related orphan receptor gamma t (RORγt), exhibiting an IC50 of 0.094 μM for the RORγt-LBD. This compound demonstrates significant biological activity in modulating RORγt signaling pathways, making it a valuable tool for research into psoriasis and related inflammatory conditions. Its use facilitates the exploration of therapeutic strategies targeting RORγt in the regulation of immune responses.
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