Fig. 1 · Structure
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RORγt modulator 2
Cat. No.
A77593
CAS
2247083-47-0
RORγt Modulator
RORγt modulator 2 is a selective modulator of retinoid-related orphan receptor γt (RORγt), exhibiting an IC50 of less than 50 nM. This compound is valuable for investigating RORγt-mediated pathologies including pain, inflammation, chronic obstructive pulmonary disease (COPD), asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative disorders, and cancer. Research on RORγt modulator 2 can contribute to understanding therapeutic approaches targeting these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2247083-47-0 |
| Applications | RORγt Modulator |
| Formula | C28H29ClN2O4S |
| Molecular Weight | 525.06 |
| SMILES | CC([C@@H]1[C@](C2=CC=C(C=C2)Cl)([H])N(C3=CC=C(C=C3)C(NCC4=CC=C(C=C4)S(CC)(=O)=O)=O)C1=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.