Fig. 1 · Structure
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RORγt modulator 3
Cat. No.
A77598
CAS
2230877-38-8
RORγt Modulator
RORγt Modulator 3 is a selective modulator of the retinoic acid receptor-related orphan receptor gamma t (RORγt). This compound exhibits significant biological activity in the modulation of immune responses, making it valuable for research into RORγt-mediated diseases, including pain, inflammation, chronic obstructive pulmonary disease (COPD), asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative disorders, and various cancer types. Its application may facilitate the development of novel therapeutic strategies targeting RORγt pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2230877-38-8 |
| Applications | RORγt Modulator |
| Formula | C25H25ClFN3O4S |
| Molecular Weight | 518.00 |
| SMILES | ClC1=C(C=CC(F)=C1)[C@H]2N(C3=CC=C(C=N3)C(NCC4=CC=C(C=C4)S(CC)(=O)=O)=O)CCOC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.