RP-001 is a potent selective agonist of the S1P1 receptor (EDG1), exhibiting an EC50 of 9 pM. This compound induces internalization and polyubiquitination of the S1P1 receptor, demonstrating significant biological activity. RP-001 is primarily utilized in research applications involving S1P signaling pathways, with minimal activity on S1P2-S1P4 and only moderate affinity for S1P5.
RP-001 is a potent selective agonist of the S1P1 receptor (EDG1), exhibiting an EC50 of 9 pM. This compound induces internalization and polyubiquitination of the S1P1 receptor, demonstrating significant biological activity. RP-001 is primarily utilized in research applications involving S1P signaling pathways, with minimal activity on S1P2-S1P4 and only moderate affinity for S1P5.
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