Fig. 1 · Structure
Documents & Downloads
RU 45144
Calmodulin Antagonist
RU 45144 is a calmodulin antagonist that inhibits the binding of estrogen receptors to calmodulin. This compound exhibits anti-estrogen activity comparable to that of tamoxifen, potentially influencing its mechanism of action through specific structural side chains. RU 45144 may also be involved in anti-proliferative effects linked to its steroid skeleton. This reagent is useful for exploring estrogen receptor signaling and related pathways in cancer research and hormonal studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 119286-92-9 |
| Applications | Calmodulin Antagonist |
| Formula | C28H37NO3 |
| Molecular Weight | 435.60 |
| SMILES | C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4C[C@H]3C5=CC=C(C=C5)OCCN(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.