Fig. 1 · Structure
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Rubratoxin A
Phosphatase Inhibitor
Rubratoxin A is a natural mycotoxin that acts as a competitive inhibitor of protein phosphatase 2A (PP2A), exhibiting an IC50 of 170 nM. This reagent is known for its ability to suppress tumor metastasis and reduce primary tumor volume in mouse xenograft models. Its specific targeting of PP2A makes it a valuable tool in cancer research, particularly in studies focused on tumor progression and signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 22467-31-8 |
| Applications | Phosphatase Inhibitor |
| Formula | C26H32O11 |
| Molecular Weight | 520.53 |
| SMILES | O=C(C1=C2[C@H](O)[C@H]([C@H](O)CCCCCC)C3=C(C[C@H]([C@@H]([C@@H]4CC=CC(O4)=O)O)C1)C(O)OC3=O)OC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.