RUSKI-201

Name: RUSKI-201
Brand: Adooq Bioscience
SKU: A44288
Rating: 5 (288 reviews)

Catalog No.: A44288

Hhat Inhibitor

RUSKI-201 is a specific inhibitor of Hedgehog acyltransferase (Hhat), exhibiting an IC50 of 0.20 μM. This compound effectively disrupts Hedgehog (Hh) signaling in cells that overexpress Sonic Hedgehog (Shh) and inhibits the palmitoylation of Hh. RUSKI-201 serves as a valuable chemical probe for investigating Hhat catalytic function and its role in cellular signaling pathways.

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Grouped product items
Size	Price	Stock
25mg	$1,275.00	In stock
50mg	$1,625.00	In stock
100mg	$2,000.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	RUSKI-201 is a specific inhibitor of Hedgehog acyltransferase (Hhat), exhibiting an IC50 of 0.20 μM. This compound effectively disrupts Hedgehog (Hh) signaling in cells that overexpress Sonic Hedgehog (Shh) and inhibits the palmitoylation of Hh. RUSKI-201 serves as a valuable chemical probe for investigating Hhat catalytic function and its role in cellular signaling pathways.

Product Information

Catalog Num	A44288
Formula	C20H27N3OS
Molecular Weight	357.51
CAS Number	1458031-48-5
SMILES	CCC(C)CNCC(N1CCC2=C(C=CS2)C1C3=NC(C)=CC=C3)=O

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