S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione-cleavable linker primarily used in antibody-drug conjugates (ADCs). This compound facilitates the covalent attachment of monoclonal antibodies to cytotoxic agents, enabling selective delivery and targeted therapy. Its unique design enhances the stability of ADCs in circulation while allowing for effective release within targeted tumor environments, making it a valuable tool in cancer research and therapeutic applications.
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione-cleavable linker primarily used in antibody-drug conjugates (ADCs). This compound facilitates the covalent attachment of monoclonal antibodies to cytotoxic agents, enabling selective delivery and targeted therapy. Its unique design enhances the stability of ADCs in circulation while allowing for effective release within targeted tumor environments, making it a valuable tool in cancer research and therapeutic applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
