S-14489 is a selective antagonist of the postsynaptic 5-HT1A receptor, exhibiting a high affinity with a pKi of 9.2. This compound can function as an agonist at 5-HT1A autoreceptors and effectively inhibit the accumulation of 5-hydroxytryptophan in the striatum. S-14489 is primarily employed in neurological research, particularly for studying disorders related to serotonin signaling.
S-14489 is a selective antagonist of the postsynaptic 5-HT1A receptor, exhibiting a high affinity with a pKi of 9.2. This compound can function as an agonist at 5-HT1A autoreceptors and effectively inhibit the accumulation of 5-hydroxytryptophan in the striatum. S-14489 is primarily employed in neurological research, particularly for studying disorders related to serotonin signaling.
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