Fig. 1 · Structure
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S 16474
NK1/NK2 Receptor Antagonist
S 16474 is a cyclic peptide that functions as an antagonist of NK1 and NK2 receptors. This compound demonstrates significant activity in modulating neurogenic inflammation. S 16474 is suitable for research applications focusing on pain pathways and inflammatory responses mediated by neurokinins.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 149250-10-2 |
| Applications | NK1/NK2 Receptor Antagonist |
| Formula | C44H47N6NaO8 |
| Molecular Weight | 810.87 |
| SMILES | O=C([C@@H](N(CC1=CC=CC=C1)C)CC2=CC=CC=C2)NC([C@H](NC(C[C@@H]3NC([C@@]([H])(N4C3=O)C5CCC4CC5)=O)=O)CC6=CN(C7=C6C=CC=C7)C(CCC(O[Na])=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.