Fig. 1 · Structure

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(S)-3,4-DCPG

mGluR Agonist

(S)-3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a), exhibiting an EC50 of 31 nM in AV12-664 cells expressing human mGluR8. This compound is valuable for studying mGluR8a-mediated signaling pathways and its role in neurological research. Its selective activation provides a useful tool for investigating potential therapeutic applications in psychiatric and neurological disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 201730-11-2
Applications mGluR Agonist
Formula C10H9NO6
Molecular Weight 239.18
Synonyms (S)-3,4-Dicarboxyphenylglycine
SMILES
OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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