(S)-CPP sodium is an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also known as BDK. By negatively regulating BCKDC activity, (S)-CPP effectively activates the complex and significantly reduces plasma concentrations of branched-chain amino acids such as leucine, isoleucine, and valine in wild-type mice. This agent is useful for research applications investigating metabolic pathways and the regulation of amino acid levels in physiological and pathological contexts.
(S)-CPP sodium is an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also known as BDK. By negatively regulating BCKDC activity, (S)-CPP effectively activates the complex and significantly reduces plasma concentrations of branched-chain amino acids such as leucine, isoleucine, and valine in wild-type mice. This agent is useful for research applications investigating metabolic pathways and the regulation of amino acid levels in physiological and pathological contexts.
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