S/GSK1349572 (Dolutegravir)

Catalog No.: A11068

HIV integrase inhibitor

S/GSK1349572 (Dolutegravir)

S/GSK1349572 (Dolutegravir) Chemical Structure

CAS NO. 1051375-16-6

S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.

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5 mg

Regular Price: $75.00

Special Price $60.00

10 mg

Regular Price: $125.00

Special Price $100.00

50 mg

Regular Price: $315.00

Special Price $252.00

100 mg

Regular Price: $495.00

Special Price $396.00

10mM * 1mL in DMSO

Regular Price: $120.00

Special Price $96.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Lea El Khoury, .et al. Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities, PeerJ Preprints, 2019, 7:e27833v1

Biological Activity

S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.
Targets
HIV integrase (Cell-free assay)
2.7 nM
In vitro DMSO Warmed: 71 mg/mL (169.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.22 mL 238.44 mL
0.5 mM 4.77 mL 23.84 mL 47.69 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11068
Actions Inhibitor
CAS No. 1051375-16-6
Formula C20H19F2N3O5
M. Wt 419.4
Purity >98%
Synonyms Dolutegravir, GSK-1349572
SMILES C[[email protected]@H]1CCO[[email protected]@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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