(S)-(+)-Ketoprofen-13C,d3 is a deuterium and carbon-13 labeled derivative of the nonsteroidal anti-inflammatory drug (NSAID) S-(+)-Ketoprofen. Primarily, it acts as a dual inhibitor of cyclooxygenase enzymes COX-1 and COX-2, demonstrating potent inhibitory activity with IC50 values of 1.9 nM and 27 nM, respectively. This stable isotope-labeled compound is valuable for pharmacokinetic studies, metabolic research, and tracing experiments in biological systems.
(S)-(+)-Ketoprofen-13C,d3 is a deuterium and carbon-13 labeled derivative of the nonsteroidal anti-inflammatory drug (NSAID) S-(+)-Ketoprofen. Primarily, it acts as a dual inhibitor of cyclooxygenase enzymes COX-1 and COX-2, demonstrating potent inhibitory activity with IC50 values of 1.9 nM and 27 nM, respectively. This stable isotope-labeled compound is valuable for pharmacokinetic studies, metabolic research, and tracing experiments in biological systems.
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