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(S)-NH2-Pyridine-piperazine(Me)-Boc

PROTAC Linker

(S)-NH2-Pyridine-piperazine(Me)-Boc is a PROTAC linker designed to facilitate the development of targeted protein degradation technologies. It serves a key role in synthesizing PROTAC molecules, such as BTK Degrader-10, which can selectively degrade target proteins via the ubiquitin-proteasome system. This compound is valuable for researchers investigating protein homeostasis, drug discovery, and therapeutics targeting protein regulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1433849-58-1
Applications	PROTAC Linker
Formula	C₁₅H₂₄N₄O₂
Molecular Weight	292.38
SMILES	O=C(N1C[C@H](C)N(C2=CC=C(N)N=C2)CC1)OC(C)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.