Fig. 1 · Structure
Documents & Downloads
(S)-p-SCN-Bn-DOTA
BFC
(S)-p-SCN-Bn-DOTA is a bifunctional chelator (BFC) that acts as a macrocyclic DOTA derivative, facilitating effective tumor pretargeting. This compound is designed for conjugating peptides and radionuclides, serving as a linker for In-111 labeled radioimmunoconjugates (RICs) utilized in single photon emission tomography (SPECT) and in vitro biodistribution studies. Its utility in radiolabeling applications enhances the development of targeted imaging agents in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1020407-41-3 |
| Applications | BFC |
| Formula | C24H33N5O8S |
| Molecular Weight | 551.61 |
| SMILES | OC(CN(CCN(CCN(CCN(C1)CC(O)=O)CC(O)=O)CC(O)=O)[C@H]1CC2=CC=C(C=C2)N=C=S)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.