Fig. 1 · Structure

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(S)-P-SCN-BN-NOTA

Chelating Agent

(S)-P-SCN-BN-NOTA is a bifunctional chelating agent that facilitates the covalent attachment of the radioactive nuclide ⁶⁴Cu to ZPDGFRβ affibody, forming the molecular probe [⁶⁴Cu]Cu-NOTA-ZPDGFRβ. This compound is crucial for applications in positron emission tomography (PET), enabling precise imaging of tumors expressing the ZPDGFRβ receptor. Its ability to effectively conjugate with radionuclides makes it valuable in the development of targeted radiotherapy and diagnostic imaging agents.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1206475-68-4
Applications Chelating Agent
Formula C20H26N4O6S
Molecular Weight 450.51
SMILES
OC(CN(CCN(CCN(C1)CC(O)=O)CC(O)=O)[C@H]1CC2=CC=C(C=C2)N=C=S)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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