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Form	MW
(S,R,R)-VH032 hydrochloride This page	467.02
(S,R,R)-VH032	430.56

(S,R,R)-VH032 hydrochloride

Ligand for E3 Ligase

(S,R,R)-VH032 hydrochloride is a selective ligand for the von Hippel-Lindau (VHL) E3 ligase. This compound facilitates the targeted degradation of proteins by enabling the formation of proteolysis-targeting chimeras (PROTACs) when conjugated to specific target protein ligands through a linker. Its unique mechanism allows for the modulation of cellular protein levels, making it a valuable tool in biochemical research and drug discovery applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2761478-98-0
Applications	Ligand for E3 Ligase
Formula	C₂₂H₃₁ClN₄O₃S
Molecular Weight	467.02
SMILES	CC1=C(SC=N1)C(C=C2)=CC=C2CNC([C@H]3N(C[C@@H](C3)O)C([C@H](N)C(C)(C)C)=O)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.