Fig. 1 · Structure
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(S)-Veludacigib
Dgkz Inhibitor
(S)-Veludacigib is a selective inhibitor of diacylglycerol kinase zeta (DGKζ), a crucial enzyme in lipid signaling pathways. This compound effectively induces the activation of phosphorylated extracellular signal-regulated kinase (pERK), which plays a significant role in cell proliferation and survival. (S)-Veludacigib is primarily utilized in research focused on cancer biology, particularly in studies exploring the modulation of signaling pathways associated with tumor growth and progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2732902-09-7 |
| Applications | Dgkz Inhibitor |
| Formula | C20H19FN4O3S |
| Molecular Weight | 414.45 |
| Synonyms | (S)-BAY 2965501 |
| SMILES | NC([C@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.