Fig. 1 · Structure
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Veludacigib
DGKζ Inhibitor
Veludacigib is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. It effectively induces phosphorylation of extracellular signal-regulated kinase (pERK), promoting downstream signaling pathways. This compound is valuable in cancer research, offering insights into the role of DGKζ in tumorigenesis and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2732902-08-6 |
| Applications | DGKζ Inhibitor |
| Formula | C20H19FN4O3S |
| Molecular Weight | 414.45 |
| Synonyms | BAY 2965501 |
| SMILES | NC([C@@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.