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S16–1029

BChE Inhibitor

S16–1029 is a selective and orally active butyrylcholinesterase (BChE) inhibitor, exhibiting IC50 values of 11.35 nM for equine BChE and 48.1 nM for human BChE. This compound is capable of crossing the blood-brain barrier (BBB), enabling it to effectively target the central nervous system (CNS). S16–1029 serves as a valuable tool for research in Alzheimer's disease (AD), contributing to the understanding of cholinergic dysfunction in neurodegenerative conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2653349-51-8
Applications	BChE Inhibitor
Formula	C₂₃H₂₅N₇O₃
Molecular Weight	447.49
SMILES	O=C(CN1C(C2=NON=C2N)=NC3=C1C=CC=C3)NC4=CC=C(CCN5CCOCC5)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.