S18-000003

Name: S18-000003
Brand: Adooq Bioscience
SKU: A19105
Rating: 5 (288 reviews)

Catalog No.: A19105

RORγt inhibitor

S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production.

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Grouped product items
Size	Price	Stock
1mg	$45.00	In stock
5mg	$120.00	In stock
10mg	$190.00	In stock
25mg	$345.00	In stock
50mg	$490.00	In stock
100mg	$690.00	In stock
500mg	$1,385.00	In stock
*10mM 1mL in DMSO**	$140.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production.

Targets

Target	Value

Product Information

Catalog Num	A19105
Formula	C26H25F3N2O4S
Molecular Weight	518.55
CAS Number	2068119-11-7
SMILES	FC1=C(NC(C(C)(C)C2=CC=C(NC(CC3=CC=C(S(CC)(=O)=O)C=C3)=O)C=C2F)=O)C=CC(F)=C1
Synonyms	S18000003, S18 000003
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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