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S1PL-IN- 2

S1PL Inhibitor

S1PL-IN-2 is a potent sphingosine-1-phosphate lyase (S1PL) inhibitor with an IC50 of 120 nM. It effectively inhibits S1PL activity by blocking the conversion of Vitamin B6 into the active cofactor pyridoxal-4-phosphate, which is essential for S1P lyase function. This compound is valuable for research in inflammation and immunology, with potential applications in studying conditions such as rheumatoid arthritis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1897406-94-8
Applications	S1PL Inhibitor
Formula	C₂₆H₃₃N₃O₃
Molecular Weight	435.56
SMILES	O=C(C1=NOC(C)=C1)NC(C2=CC=CC=C2)CNCC3=CC(C)=C(OCCCC)C=C3C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.