S1R Agonist 2 is a selective sigma-1 receptor (S1R) agonist, demonstrating a binding affinity of 1.1 nM for S1R and 88 nM for sigma-2 receptor (S2R). This compound exhibits significant neuroprotective effects against reactive oxygen species (ROS) and N-methyl-D-aspartate (NMDA)-induced neurotoxicity. Due to its targeted action on the S1R, S1R Agonist 2 is valuable for research focusing on neurodegenerative diseases and neuronal protection mechanisms.
S1R Agonist 2 is a selective sigma-1 receptor (S1R) agonist, demonstrating a binding affinity of 1.1 nM for S1R and 88 nM for sigma-2 receptor (S2R). This compound exhibits significant neuroprotective effects against reactive oxygen species (ROS) and N-methyl-D-aspartate (NMDA)-induced neurotoxicity. Due to its targeted action on the S1R, S1R Agonist 2 is valuable for research focusing on neurodegenerative diseases and neuronal protection mechanisms.
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