Fig. 1 · Structure
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S32826
Autotaxin Inhibitor
S32826 is a potent inhibitor of autotaxin, exhibiting an IC50 of 8.8 nM. This compound effectively targets various autotaxin isoforms, including α, β, and γ, demonstrating similar inhibitory effects across these forms. S32826 also plays a significant role in inhibiting lysophosphatidic acid (LPA) release from adipocytes, making it valuable for studies related to lipid signaling and metabolic research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1096770-84-1 |
| Applications | Autotaxin Inhibitor |
| Formula | C21H36NO4P |
| Molecular Weight | 397.49 |
| SMILES | O=C(NC1=CC=C(C=C1)CP(O)(O)=O)CCCCCCCCCCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.