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Biological Activity
S55746 hydrochloride (BLC201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.38 mL | 66.91 mL | 133.82 mL |
| 0.5 mM | 2.68 mL | 13.38 mL | 26.76 mL |
| 1 mM | 1.34 mL | 6.69 mL | 13.38 mL |
| 5 mM | 0.27 mL | 1.34 mL | 2.68 mL |
*The above data is based on the productmolecular weight 747.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21811 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1448525-91-4 |
| Formula | C43H43ClN4O6 |
| M. Wt | 747.28 |
| Purity | >98% |
| Synonyms | BLC201 (hydrochloride), BLC 201, BLC-201; S 55746, S-55746 |
| SMILES | O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[[email protected]]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
United StatesAdooq Bioscience
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