Fig. 1 · Structure
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S9-A13
SLC26A9 Inhibitor
S9-A13 is a selective inhibitor of the SLC26A9 transporter, exhibiting an IC50 of 90.9 nM. This compound demonstrates the ability to inhibit SLC26A9 chloride currents in cells that do not express CFTR, while showing no inhibitory effects on other members of the SLC26 family, including SLC26A3, SLC26A4, and SLC26A6. S9-A13 is valuable for research applications focused on ion transport mechanisms and the physiological role of SLC26A9.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1223771-84-3 |
| Applications | SLC26A9 Inhibitor |
| Formula | C20H18ClN3O2S |
| Molecular Weight | 399.89 |
| SMILES | O=C1NC2=C(C(C1)C(C3=CC=C(C)S3)=O)C(C)=NN2C4=CC=C(C)C(Cl)=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.