Fig. 1 · Structure
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Sabiporide hydrochloride
NHE-1 Inhibitor
Sabiporide hydrochloride is a potent NHE-1 inhibitor with a Ki of 50 nM. It exhibits significant cardioprotective and neuroprotective effects, primarily by preventing glutamate- or NMDA-induced neuronal cell death. This compound is useful in research applications focusing on ischemic injury and neurodegenerative diseases, contributing to the understanding of cellular mechanisms involved in cardiac and neuronal protection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 324758-66-9 |
| Applications | NHE-1 Inhibitor |
| Formula | C18H20ClF3N6O2 |
| Molecular Weight | 444.84 |
| Synonyms | BIIB 722 hydrochloride |
| SMILES | O=C(NC(N)=N)C1=CC=C(N2CCN(C(C3=CC=CN3)=O)CC2)C(C(F)(F)F)=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.