Fig. 1 · Structure
Documents & Downloads
SAR113945
Cat. No.
A79479
CAS
869796-50-9
IKK-β Inhibitor
SAR113945 is a highly potent inhibitor of IKK-β, exhibiting an IC50 value of 0.4 nM. This compound is primarily utilized in research focusing on inflammatory pathways and oncogenic processes. Its efficacy makes it a valuable tool for investigating the role of IKK-β in various disease states, particularly in understanding mechanisms underlying inflammation and cancer progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 869796-50-9 |
| Applications | IKK-β Inhibitor |
| Formula | C28H25N7O3 |
| Molecular Weight | 507.55 |
| SMILES | N(C[C@H](NC(=O)C=1C=C2C(=CC1)NC(=C2)C3=NC(NC)=NC=C3)C(O)=O)(C4=CC=CC=C4)C5=CC=CC=N5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.