Fig. 1 · Structure

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SARS-CoV-2-IN-102

SARS-CoV-2 Antiviral Agent

SARS-CoV-2-IN-102 is a potent inhibitor of the SARS-CoV papain-like protease (PLpro), demonstrating an IC50 of less than 100 nM. This compound exhibits significant antiviral activity against SARS-CoV-2, making it a valuable tool for research in the development of therapeutic agents targeting COVID-19. Its mechanism of action involves the disruption of viral replication, thereby providing insights into antiviral strategies and the efficacy of protease inhibitors in combating SARS-CoV-2 infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3055041-73-8
Applications SARS-CoV-2 Antiviral Agent
Formula C29H34F2N6O2
Molecular Weight 536.62
SMILES
CC1=C(C=C(C=C1)OCCN(C)C)C(N[C@@H](C2=CC(C3=CN(N=C3)CC(F)F)=CC(C4=CN(N=C4)C)=C2)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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