SARS-CoV-2-IN-102

Catalog No.: A53520
SARS-CoV-2 Antiviral Agent
SARS-CoV-2-IN-102 is a potent inhibitor of the SARS-CoV papain-like protease (PLpro), demonstrating an IC50 of less than 100 nM. This compound exhibits significant antiviral activity against SARS-CoV-2, making it a valuable tool for research in the development of therapeutic agents targeting COVID-19. Its mechanism of action involves the disruption of viral replication, thereby providing insights into antiviral strategies and the efficacy of protease inhibitors in combating SARS-CoV-2 infections.
Grouped product items
Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSARS-CoV-2-IN-102 is a potent inhibitor of the SARS-CoV papain-like protease (PLpro), demonstrating an IC50 of less than 100 nM. This compound exhibits significant antiviral activity against SARS-CoV-2, making it a valuable tool for research in the development of therapeutic agents targeting COVID-19. Its mechanism of action involves the disruption of viral replication, thereby providing insights into antiviral strategies and the efficacy of protease inhibitors in combating SARS-CoV-2 infections.
Product Information
Catalog NumA53520
FormulaC29H34F2N6O2
Molecular Weight536.62
CAS Number3055041-73-8
SMILESCC1=C(C=C(C=C1)OCCN(C)C)C(N[C@@H](C2=CC(C3=CN(N=C3)CC(F)F)=CC(C4=CN(N=C4)C)=C2)C)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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