Fig. 1 · Structure
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SARS-CoV-2-IN-11
3CLpro Inhibitor
SARS-CoV-2-IN-11 is a potent, nontoxic inhibitor of the SARS-CoV-2 3C-like protease (3CLpro), exhibiting IC50 and EC50 values of 0.17 nM and 1.45 nM, respectively. This enzyme plays a crucial role in the viral replication process, making it a significant target for therapeutic intervention. SARS-CoV-2-IN-11 is a valuable tool for research focused on the development of effective, SARS-CoV-2-specific antiviral agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2722635-28-9 |
| Applications | 3CLpro Inhibitor |
| Formula | C27H38F2N3NaO8S |
| Molecular Weight | 625.66 |
| SMILES | O=C(NCC1)[C@@H]1C[C@@H](C(O)S(=O)(O[Na])=O)NC([C@H](CC(C)C)NC(OC(C2=CC=CC=C2)C3CCC(F)(CC3)F)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.