SARS-CoV-2-IN-59

Catalog No.: A53374
SARS-CoV-2 Inhibitor
SARS-CoV-2-IN-59 is a non-peptide small molecule inhibitor targeting the main protease (Mpro) of SARS-CoV-2. This imidazoline derivative demonstrates significant interaction with critical residues in the Mpro active site, including Met 165, Gln 166, His 41, and Gln 189. SARS-CoV-2-IN-59 is a valuable tool for studying viral pathogenesis and potential therapeutic strategies against COVID-19.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSARS-CoV-2-IN-59 is a non-peptide small molecule inhibitor targeting the main protease (Mpro) of SARS-CoV-2. This imidazoline derivative demonstrates significant interaction with critical residues in the Mpro active site, including Met 165, Gln 166, His 41, and Gln 189. SARS-CoV-2-IN-59 is a valuable tool for studying viral pathogenesis and potential therapeutic strategies against COVID-19.
Product Information
Catalog NumA53374
FormulaC10H9N3
Molecular Weight171.20
CAS Number850786-33-3
SMILESN#CC1=CC=C(C2=NCCN2)C=C1
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