SARS-CoV-2-IN-97 is a specific inhibitor targeting the SARS-CoV-2 Nsp15 endoribonuclease, demonstrating an IC50 of 53.5 μM. This compound shows low cytotoxicity in A549-AT cells, with an IC50 of 134 μM, making it a valuable tool for studying SARS-CoV-2 biology and antiviral strategies. Its selective inhibition could aid in the development of therapeutic approaches against COVID-19.
SARS-CoV-2-IN-97 is a specific inhibitor targeting the SARS-CoV-2 Nsp15 endoribonuclease, demonstrating an IC50 of 53.5 μM. This compound shows low cytotoxicity in A549-AT cells, with an IC50 of 134 μM, making it a valuable tool for studying SARS-CoV-2 biology and antiviral strategies. Its selective inhibition could aid in the development of therapeutic approaches against COVID-19.
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