SARS-CoV-2 Mpro-IN-31

Catalog No.: A53359
SARS-CoV-2 Mpro Inhibitor
SARS-CoV-2 Mpro-IN-31 is a potent inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an IC50 of 11 nM. This compound also significantly inhibits the enzymatic activity of cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively. Its high specificity and efficacy make SARS-CoV-2 Mpro-IN-31 a valuable tool for research related to coronavirus pathology and enzyme regulation.
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Size Stock
5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSARS-CoV-2 Mpro-IN-31 is a potent inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an IC50 of 11 nM. This compound also significantly inhibits the enzymatic activity of cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively. Its high specificity and efficacy make SARS-CoV-2 Mpro-IN-31 a valuable tool for research related to coronavirus pathology and enzyme regulation.
Product Information
Catalog NumA53359
FormulaC31H34Cl2N4O7
Molecular Weight645.53
CAS Number870153-73-4
SMILESCOC1=C2C=C(NC2=CC=C1)C(N[C@H](C(N[C@H](C(COC(C3=C(C=CC=C3Cl)Cl)=O)=O)C[C@@H]4CCNC4=O)=O)CC(C)C)=O
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