SARS-CoV-2 Mpro-IN-45 is a potent inhibitor of the main protease (Mpro) of SARS-CoV-2, with IC50 values of 0.12 μM for HCoV-OC43 Mpro and 0.16 μM specifically for SARS-CoV-2 Mpro. This compound demonstrates effective antiviral activity, making it valuable for research into therapeutic strategies against COVID-19 and related coronaviruses. Its oral bioavailability further enhances its potential applications in drug development and infectious disease studies.
SARS-CoV-2 Mpro-IN-45 is a potent inhibitor of the main protease (Mpro) of SARS-CoV-2, with IC50 values of 0.12 μM for HCoV-OC43 Mpro and 0.16 μM specifically for SARS-CoV-2 Mpro. This compound demonstrates effective antiviral activity, making it valuable for research into therapeutic strategies against COVID-19 and related coronaviruses. Its oral bioavailability further enhances its potential applications in drug development and infectious disease studies.
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