Fig. 1 · Structure
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SARS-CoV-2 nsp13-IN-1
Nsp13 Inhibitor
SARS-CoV-2 nsp13-IN-1 is a selective inhibitor of the non-structural protein 13 (nsp13) from the SARS-CoV-2 virus, demonstrating significant activity against ssDNA-dependent ATPase with an IC50 value of 6 μM. Notably, it does not affect ssDNA-independent ATPase activity, making it a valuable tool for investigating the mechanistic role of nsp13 in viral replication. This compound is suitable for research applications focused on COVID-19 therapeutics and the exploration of antiviral strategies targeting nsp13.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1005304-44-8 |
| Applications | Nsp13 Inhibitor |
| Formula | C27H20N4O2 |
| Molecular Weight | 432.47 |
| SMILES | CC1=NC2=NC=CC=C2C(N1C3=CC=C(C=C3)NC(C4=CC=C(C=C4)C5=CC=CC=C5)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.