Fig. 1 · Structure
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SARS-CoV-2 nsp3-IN-2
Mac1 Inhibitor
SARS-CoV-2 nsp3-IN-2 is an inhibitor of the macrodomain (Mac1), exhibiting an IC50 value of 180 μM. This small molecule chemical probe is intended for research applications focused on viral mechanisms and host interactions, facilitating the study of SARS-CoV-2 pathogenesis. Its unique properties allow for the exploration of viral replication processes and potential therapeutic strategies targeting coronavirus infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2038858-11-4 |
| Applications | Mac1 Inhibitor |
| Formula | C10H12N4O2 |
| Molecular Weight | 220.23 |
| SMILES | CN(C1=NC=NC2=C1C=CN2)CCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.