Fig. 1 · Structure
Documents & Downloads
SB 206553 hydrochloride
5-HT Receptor Antagonist
SB 206553 hydrochloride is a selective antagonist targeting the 5-HT2B and 5-HT2C receptors. It exhibits high affinity, with a rat 5-HT2B pA2 value of 8.89 and a human 5-HT2C pKi value of 7.92, indicating its effectiveness in modulating serotonin pathways. This compound demonstrates anxiolytic-like properties, making it a valuable tool in research exploring anxiety disorders and related therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1197334-04-5 |
| Applications | 5-HT Receptor Antagonist |
| Formula | C17H17ClN4O |
| Molecular Weight | 328.80 |
| SMILES | O=C(N1C(C(CC1)=C2)=CC3=C2N(C)C=C3)NC4=CC=CN=C4.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.