SB 206553 hydrochloride

Catalog No.: A46023
5-HT Receptor Antagonist
SB 206553 hydrochloride is a selective antagonist targeting the 5-HT2B and 5-HT2C receptors. It exhibits high affinity, with a rat 5-HT2B pA2 value of 8.89 and a human 5-HT2C pKi value of 7.92, indicating its effectiveness in modulating serotonin pathways. This compound demonstrates anxiolytic-like properties, making it a valuable tool in research exploring anxiety disorders and related therapeutic interventions.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$100.00
In stock
10mg
$165.00
In stock
25mg
$335.00
In stock
50mg
$475.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSB 206553 hydrochloride is a selective antagonist targeting the 5-HT2B and 5-HT2C receptors. It exhibits high affinity, with a rat 5-HT2B pA2 value of 8.89 and a human 5-HT2C pKi value of 7.92, indicating its effectiveness in modulating serotonin pathways. This compound demonstrates anxiolytic-like properties, making it a valuable tool in research exploring anxiety disorders and related therapeutic interventions.
Product Information
Catalog NumA46023
FormulaC17H17ClN4O
Molecular Weight328.80
CAS Number1197334-04-5
SMILESO=C(N1C(C(CC1)=C2)=CC3=C2N(C)C=C3)NC4=CC=CN=C4.[H]Cl
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