SB 431542

Catalog No.: A10826
TGF-beta/Smad inhibitor
SB 431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I ALK receptors ALK4, ALK5, and ALK7 .
Grouped product items
Product Name Price Stock Qty
SB 431542 10mg
Special Price $64.00 Regular Price $80.00
In stock
SB 431542 25mg
Special Price $128.00 Regular Price $160.00
In stock
SB 431542 50mg
Special Price $240.00 Regular Price $300.00
In stock
SB 431542 100mg
Special Price $448.00 Regular Price $560.00
In stock
SB 431542 10mM * 1mL in DMSO
Special Price $64.00 Regular Price $80.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's SB 431542 has been cited by 3 publications
  • Huong Pham, .et al. , Biotechnol Bioprocess Eng, 2020, ID: 222137835
  • Tamara Chamberlin, .et al. , FASEB J, 2020, Jun;34(6):8611-8624 PMID: 32359100
  • Satoshi Endo, .et al. , Nutr Res, 2019, 4 November
  • Biological Activity
    Discription SB 431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I ALK receptors ALK4, ALK5, and ALK7 .
    Targets
    Target Value
    Product Information
    Catalog Num A10826
    Formula C22H16N4O3
    Molecular Weight 384.4
    CAS Number 301836-41-9
    SMILES C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
    Synonyms SB-431542, SB431542
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 75 mg/mL (195.11 mM)
    Water Insoluble
    Ethanol 3 mg/mL (7.8 mM)
    In vivo 2% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.01 mL 130.07 mL 260.15 mL
    0.5 mM 5.2 mL 26.01 mL 52.03 mL
    1 mM 2.6 mL 13.01 mL 26.01 mL
    5 mM 0.52 mL 2.6 mL 5.2 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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