Fig. 1 · Structure
Documents & Downloads
SB 452533
Cat. No.
A68750
CAS
459429-39-1
TRPV1 Antagonist
SB 452533 is a potent and selective antagonist of the TRPV1 ion channel. It demonstrates a pKb of 7.8, indicating strong binding affinity and inhibitory activity. This compound is primarily utilized in research applications related to pain modulation and inflammation, offering insights into the role of TRPV1 in nociception and sensory neurons. SB 452533 is an essential tool for studying pain pathways and developing potential analgesic therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 459429-39-1 |
| Applications | TRPV1 Antagonist |
| Formula | C18H22BrN3O |
| Molecular Weight | 376.29 |
| SMILES | O=C(NCCN(CC)C1=CC=CC(C)=C1)NC2=CC=CC=C2Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.