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SB5-171

PfCLK3 Inhibitor

SB5-171 is a covalent inhibitor of PfCLK3, exhibiting IC50 values in the range of 10-12 nM. This compound demonstrates significant antiparasitic activity, making it a valuable tool in malaria research. Its selective inhibition of PfCLK3 provides insights into the mechanistic pathways of Plasmodium falciparum, aiding in the development of novel therapeutic strategies against malaria.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3088376-92-2
Applications	PfCLK3 Inhibitor
Formula	C₂₉H₃₁N₅O₇S
Molecular Weight	593.65
SMILES	O=C(O)C1=CC=C(C2=C3C(NC(C4=CC(CN5CCN(C(COS(=O)(NC)=O)=O)CC5)=CC=C4OC)=C3)=NC=C2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.