SBP-0636457 is a potent SMAC mimetic that functions as an inhibitor of inhibitor of apoptosis (IAP) proteins. By selectively binding to the BIR domains of IAPs, it exhibits a binding affinity with a Ki of 0.27 μM. This compound is primarily utilized in research related to solid tumors and hematologic malignancies, highlighting its potential in cancer therapeutics.
SBP-0636457 is a potent SMAC mimetic that functions as an inhibitor of inhibitor of apoptosis (IAP) proteins. By selectively binding to the BIR domains of IAPs, it exhibits a binding affinity with a Ki of 0.27 μM. This compound is primarily utilized in research related to solid tumors and hematologic malignancies, highlighting its potential in cancer therapeutics.
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