SC-43

Name: SC-43
Brand: Adooq Bioscience
SKU: A22295
Rating: 5 (288 reviews)

Catalog No.: A22295

SHP-1 (PTPN6) agonist

SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects.

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SC-43 1400989-25-4 SHP-1 (PTPN6) agonist

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Grouped product items
Size	Price	Stock
1mg	$90.00	In stock
5mg	$190.00	In stock
10mg	$280.00	In stock
25mg	$530.00	In stock
50mg	$760.00	In stock
100mg	$980.00	In stock
*10mM 1mL in DMSO**	$220.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects.

Product Information

Catalog Num	A22295
Formula	C21H13ClF3N3O2
Molecular Weight	431.8
CAS Number	1400989-25-4
SMILES	O=C(NC1=CC=CC(OC2=CC=C(C#N)C=C2)=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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