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SC-45662

Name: SC-45662
Brand: Adooq Bioscience
SKU: A76489
Availability: OutOfStock

Cat. No. A76489 CAS 135133-84-5

5-lipoxygenase Inhibitor

SC-45662 is a selective inhibitor of 5-lipoxygenase, a key enzyme involved in leukotriene biosynthesis. This compound effectively suppresses the activation of monocytes in response to phytohemagglutinin (PHA) and reduces superoxide production in neutrophils, highlighting its potential impact on inflammation. SC-45662 has also demonstrated the ability to ameliorate early alterations in lung mechanics and alleviate pulmonary hypertension in sheep models of compromised lung function. Its applications include research into immune system disorders, respiratory diseases, and related pathological conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	135133-84-5
Applications	5-lipoxygenase Inhibitor
Formula	C₂₀H₃₂O₄S
Molecular Weight	368.53
SMILES	O=C(O)CO[C@@H](C)[C@H](SC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.