SC 51089 is a selective antagonist of the prostaglandin E2 EP1 receptor, characterized by binding affinities with Kis of 1.3 μM for EP1, and higher affinities for TP, EP3, and FP receptors, with Kis of 11.2, 17.5, and 61.1 μM, respectively. This compound has demonstrated neuroprotective activity, making it valuable for research applications focused on neuroinflammation and pain signaling pathways. SC 51089 offers potential insights into EP1 receptor-related diseases and therapeutic interventions.
SC 51089 is a selective antagonist of the prostaglandin E2 EP1 receptor, characterized by binding affinities with Kis of 1.3 μM for EP1, and higher affinities for TP, EP3, and FP receptors, with Kis of 11.2, 17.5, and 61.1 μM, respectively. This compound has demonstrated neuroprotective activity, making it valuable for research applications focused on neuroinflammation and pain signaling pathways. SC 51089 offers potential insights into EP1 receptor-related diseases and therapeutic interventions.
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