Fig. 1 · Structure
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SCFSkp2-IN-2
Skp2 Inhibitor
SCFSkp2-IN-2 is a selective inhibitor of Skp2, exhibiting a KD value of 28.77 μM. This compound induces apoptosis in non-small cell lung cancer (NSCLC) cells, demonstrating significant antitumor activity. SCFSkp2-IN-2 is valuable for research applications focused on understanding the role of Skp2 in cancer biology and exploring potential therapeutic strategies for NSCLC.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1375060-02-8 |
| Applications | Skp2 Inhibitor |
| Formula | C17H20N4O2 |
| Molecular Weight | 312.37 |
| SMILES | CCN(C1=CC(O)=C(C=C1)/C=N/NC(C2=CN=CC=C2)=O)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.